ICD-10 Code C25.1 – Malignant neoplasm of body of pancreas (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code C25.1 – Malignant neoplasm of body of pancreas
What it is
C25.1 identifies a malignant tumor arising in the body of the pancreas. Use it when documentation specifies the pancreatic body as the primary site.
Clinical signs
Clinical features vary; refer to documentation. Pancreatic cancers may present with abdominal or back pain, weight loss, jaundice, or imaging evidence of a pancreatic mass.
When to use this code
Use C25.1 when the provider documents primary cancer of the pancreatic body, including confirmed pathology or imaging-supported diagnosis. It also applies when the record clearly localizes the malignancy to the body of the pancreas. If the site is described only as pancreas or is uncertain, check documentation.
Do not use for
Do not use this code for malignant neoplasms of the head, tail, or other specified pancreatic sites. Do not use it for metastatic disease to the pancreas unless the pancreas is the documented primary site.
Coding tip
Verify the exact anatomic site in the pathology, operative, or oncology note before assigning C25.1.