ICD-10 Code C25 – Malignant neoplasm of pancreas (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code C25 – Malignant neoplasm of pancreas
What it is
C25 identifies a malignant tumor arising in the pancreas. Use it when the record documents pancreatic cancer but does not specify a more detailed site or behavior.
Clinical signs
Clinical features vary; refer to documentation. Commonly noted findings include abdominal pain, jaundice, weight loss, or a pancreatic mass confirmed by imaging, pathology, or specialist assessment.
When to use this code
Use C25 when the provider documents primary pancreatic malignancy and no more specific subcategory is available. It also fits nonspecific charting such as “pancreatic cancer” or “malignant neoplasm of pancreas.” Check documentation for exact anatomic site, histology, and whether the tumor is primary or secondary.
Do not use for
Do not use C25 for benign pancreatic lesions, cysts, or pancreatitis. If the record identifies metastatic disease to the pancreas or a different primary site, code that condition instead.
Coding tip
Verify whether the chart specifies head, body, tail, or other pancreatic site before assigning the less specific code.