ICD-10 Code I25.752 – Atherosclerosis of native coronary artery of transplanted heart with refractory angina pectoris (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code I25.752 – Atherosclerosis of native coronary artery of transplanted heart with refractory angina pectoris
What it is
This code identifies atherosclerotic narrowing in the native coronary arteries of a transplanted heart, with angina that persists despite usual therapy. It reflects chronic ischemic heart disease in a transplant recipient.
Clinical signs
Patients may report ongoing chest pain or ischemic discomfort that does not improve with standard antianginal management. Documentation should support both coronary atherosclerosis in the transplanted heart and refractory angina; clinical features vary, refer to documentation.
When to use this code
Use this code when the provider documents atherosclerosis of the native coronary arteries in a transplanted heart and specifies refractory angina pectoris. It is appropriate when the condition is confirmed in the record, such as by cardiology assessment, imaging, or catheterization. If the note does not clearly state refractory angina, check documentation.
Do not use for
Do not use this code for angina without documented refractory status, or for coronary disease in a non-transplanted heart. If the chart describes another ischemic heart disease category, choose the more specific documented diagnosis.
Coding tip
Verify that the record links the native coronary artery disease to the transplanted heart before assigning I25.752.