ICD-10 Code B45.7 – Disseminated cryptococcosis (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code B45.7 – Disseminated cryptococcosis
What it is
B45.7 identifies disseminated cryptococcosis, a widespread infection caused by Cryptococcus species. Use it when the organism has spread beyond one site, often affecting multiple organs or the central nervous system.
Clinical signs
Clinical features vary; refer to documentation. Commonly documented findings include systemic illness with involvement of more than one body site, and possible neurologic, pulmonary, or bloodstream manifestations.
When to use this code
Use this code when the record clearly states disseminated cryptococcosis or cryptococcal infection with spread to multiple sites. It also fits cases described as systemic cryptococcosis when the documentation supports dissemination.
If the note only identifies a localized cryptococcal infection, choose the more specific site code instead. When the extent is unclear, check documentation before assigning B45.7.
Do not use for
Do not use it for isolated pulmonary, meningeal, or cutaneous cryptococcosis unless the infection is documented as disseminated. Avoid it when the chart does not confirm spread beyond a single site.
Coding tip
Look for explicit wording such as “disseminated,” “systemic,” or “multisite” cryptococcosis before assigning B45.7.