ICD-10 Code L25.1 – Unspecified contact dermatitis due to drugs in contact with skin (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Unspecified contact dermatitis due to drugs in contact with skin is L25.1.
2026 ICD-10-CM Diagnosis Code L25.1 – Unspecified contact dermatitis due to drugs in contact with skin

What it is

This code identifies contact dermatitis caused by a drug or medication that touched the skin, when the exact dermatitis type is not specified. Use it for a skin reaction linked to direct exposure, not ingestion or injection.

Clinical signs

Typical findings include localized redness, itching, burning, swelling, or a rash at the site of contact. Clinical features vary; refer to documentation if the record does not clearly describe the skin reaction.

When to use this code

Use this code when the provider documents contact dermatitis from a drug applied to or handled by the skin, but does not name the reaction more specifically. It also fits cases where the medication exposure is clear, yet the dermatitis is not otherwise classified. Check documentation for the exact agent and site.

Do not use for

Do not use it for dermatitis due to food, inhaled substances, or systemic drug reactions. If the chart describes a more specific contact dermatitis type or a different cause, code that instead.

Coding tip

Confirm that the drug exposure was topical or skin contact related before assigning L25.1.

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