ICD-10 Code K85.31 – Drug induced acute pancreatitis with uninfected necrosis (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Drug induced acute pancreatitis with uninfected necrosis is K85.31.
2026 ICD-10-CM Diagnosis Code K85.31 – Drug induced acute pancreatitis with uninfected necrosis

What it is

This code identifies an acute inflammation of the pancreas caused by a drug, with pancreatic tissue death present but no infection in the necrotic area. Use it when documentation clearly links the pancreatitis to medication exposure.

Clinical signs

Typical findings include acute abdominal pain, nausea, vomiting, and imaging or clinical evidence of pancreatic necrosis. Clinical features vary; refer to documentation for confirmation of the drug cause and the uninfected necrosis.

When to use this code

Use K85.31 when the record states acute pancreatitis is drug induced and necrosis is present without infection. It fits inpatient or outpatient documentation that names the offending drug or clearly attributes the episode to medication. If the cause or necrosis status is unclear, check documentation.

Do not use for

Do not use this code for pancreatitis without necrosis, infected pancreatic necrosis, or pancreatitis from non-drug causes. If the provider does not document a drug cause, do not assume it.

Coding tip

Verify both elements in the note: drug causation and uninfected necrosis; if either is missing, query or code to the documented specificity.

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