ICD-10 Code K76.81 – Hepatopulmonary syndrome (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code K76.81 – Hepatopulmonary syndrome
What it is
Hepatopulmonary syndrome is a complication of liver disease where abnormal blood vessel changes in the lungs cause low oxygen levels. Use this code when the diagnosis is documented and linked to liver disease.
Clinical signs
Typical findings include shortness of breath, low oxygen saturation, and worsening symptoms when upright. Clinical features vary; refer to documentation.
When to use this code
Use K76.81 when the provider documents hepatopulmonary syndrome as the reason for hypoxemia or as a confirmed complication of cirrhosis or other liver disease. It may also apply when the record states intrapulmonary vascular dilatation with liver disease. Check documentation if the note only mentions dyspnea or hypoxemia without the syndrome.
Do not use for
Do not use this code for liver disease alone, pulmonary hypertension, or nonspecific respiratory symptoms without hepatopulmonary syndrome. If the diagnosis is uncertain, check documentation.
Coding tip
Assign K76.81 only when the provider clearly links the lung oxygenation problem to liver disease.