ICD-10 Code K74.3 – Primary biliary cirrhosis (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Primary biliary cirrhosis is K74.3.
2026 ICD-10-CM Diagnosis Code K74.3 – Primary biliary cirrhosis

What it is

K74.3 identifies primary biliary cirrhosis, now commonly called primary biliary cholangitis. It refers to a chronic autoimmune disease that slowly damages the small bile ducts in the liver.

Clinical signs

Clinical features vary; refer to documentation. Commonly documented findings include chronic cholestatic liver disease, pruritus, fatigue, and evidence of bile duct injury or cirrhosis on evaluation.

When to use this code

Use K74.3 when the provider documents primary biliary cirrhosis or primary biliary cholangitis as the diagnosis. Apply it for confirmed chronic autoimmune bile duct disease, including cases described as early or established cirrhosis. Do not infer the diagnosis from abnormal liver tests alone; check documentation.

Do not use for

Do not use this code for other causes of cirrhosis, hepatitis, or nonspecific cholestasis. If the record only says “liver disease” or “elevated liver enzymes,” check documentation.

Coding tip

Code only when the provider clearly links the condition to primary biliary disease, and follow any documented terminology changes such as “primary biliary cholangitis.”

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