ICD-10 Code I88.0 – Nonspecific mesenteric lymphadenitis (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code I88.0 – Nonspecific mesenteric lymphadenitis
What it is
I88.0 identifies nonspecific inflammation of the mesenteric lymph nodes, usually in the abdomen. Use it when the record states mesenteric lymphadenitis and does not name a more specific cause.
Clinical signs
Clinical features vary; refer to documentation. Patients may have abdominal pain, tenderness, or symptoms that resemble appendicitis, but the chart should support mesenteric lymph node inflammation.
When to use this code
Use this code when the clinician documents nonspecific mesenteric lymphadenitis, mesenteric adenitis, or similar wording without a more precise etiology. It may appear after imaging, examination, or surgical evaluation. If the note identifies a different underlying condition, code that diagnosis instead.
Do not use for
Do not use I88.0 for generalized lymphadenitis, lymph node enlargement without inflammation, or a clearly documented specific infectious cause. Check documentation if the chart only mentions abdominal pain.
Coding tip
Code I88.0 only when the provider links the finding to mesenteric lymphadenitis, not when it is merely suspected.