ICD-10 Code I67.850 – Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code I67.850 – Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy
What it is
This code identifies CADASIL, a hereditary small-vessel brain disease that can cause recurrent strokes and white-matter changes. Use it when the diagnosis is documented as cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy.
Clinical signs
Typical findings include migraine with aura, recurrent subcortical ischemic events, cognitive decline, mood changes, and characteristic white-matter abnormalities on brain imaging. Clinical features vary; refer to documentation.
When to use this code
Use I67.850 when the provider documents CADASIL, whether the patient is being evaluated for known disease or followed for ongoing neurologic manifestations. It is also appropriate when imaging and genetic or specialist documentation support the diagnosis. If the record only mentions stroke or leukoencephalopathy without CADASIL, check documentation.
Do not use for
Do not use this code for nonspecific cerebral infarction, general dementia, or white-matter disease without a documented CADASIL diagnosis. Check documentation if the chart uses a family history or suspected disorder only.
Coding tip
Code the confirmed hereditary diagnosis, not just the presenting neurologic symptom, and verify that CADASIL is explicitly documented.