ICD-10 Code H21.81 – Floppy iris syndrome (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code H21.81 – Floppy iris syndrome
What it is
H21.81 identifies floppy iris syndrome, a condition in which the iris behaves abnormally during eye surgery. It is used when documentation specifically names this syndrome.
Clinical signs
Clinical features vary; refer to documentation. Commonly noted findings include a floppy, billowing iris, tendency for iris prolapse, and progressive pupil constriction during cataract surgery.
When to use this code
Use H21.81 when the ophthalmology record clearly documents floppy iris syndrome, often in the setting of intraoperative iris instability. Code it when the surgeon identifies the syndrome as a diagnosis or operative finding. If the note only mentions small pupil or difficult dilation without this term, check documentation.
Do not use for
Do not use this code for routine cataract surgery, generic iris abnormalities, or postoperative inflammation unless floppy iris syndrome is specifically documented. Do not assume it from medication history alone.
Coding tip
Match the exact operative wording; if the surgeon does not document floppy iris syndrome, verify before assigning H21.81.