ICD-10 Code H21.561 – Pupillary abnormality, right eye (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Pupillary abnormality, right eye is H21.561.
2026 ICD-10-CM Diagnosis Code H21.561 – Pupillary abnormality, right eye

What it is

This code identifies an abnormal pupil finding limited to the right eye. It is used when the pupil’s size, shape, or reaction is not normal and the documentation specifies the right side.

Clinical signs

Findings may include an irregularly shaped pupil, unequal pupil size, or abnormal response to light in the right eye. Clinical features vary; refer to documentation.

When to use this code

Use H21.561 when the provider documents a pupillary abnormality in the right eye without assigning a more specific diagnosis. It is appropriate for office, emergency, or ophthalmology notes that clearly identify the right eye. Check documentation if the abnormality is described only as bilateral or unspecified.

Do not use for

Do not use this code for left-eye or bilateral pupillary abnormalities, or when the chart does not specify the right eye. If the abnormal pupil is part of a broader condition, code the documented underlying diagnosis instead.

Coding tip

Confirm laterality and whether the note describes a standalone pupillary abnormality before assigning H21.561.

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