ICD-10 Code H21.261 – Iris atrophy (essential) (progressive), right eye (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Iris atrophy (essential) (progressive), right eye is H21.261.
2026 ICD-10-CM Diagnosis Code H21.261 – Iris atrophy (essential) (progressive), right eye

What it is

H21.261 identifies progressive, essential atrophy of the iris in the right eye. Use it when documentation specifies a degenerative iris thinning or loss of tissue, limited to the right eye.

Clinical signs

Clinical features vary; refer to documentation. Typical findings may include visible thinning of the iris, transillumination defects, or irregular iris architecture noted on eye examination.

When to use this code

Use this code when the provider documents iris atrophy as essential or progressive and clearly states the right eye. It is appropriate for ophthalmology notes, problem lists, or assessments that identify the condition without another primary cause. If the laterality is not documented, check documentation before assigning a unilateral code.

Do not use for

Do not use this code for iris changes due to trauma, surgery, inflammation, or another specified disorder. If the record does not confirm right-eye involvement or the diagnosis is uncertain, check documentation.

Coding tip

Confirm both the diagnosis wording and laterality in the ophthalmology note before coding H21.261.

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