ICD-10 Code H21.249 – Degeneration of pupillary margin, unspecified eye (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code H21.249 – Degeneration of pupillary margin, unspecified eye
What it is
This code identifies degenerative change at the pupillary margin of the iris in an unspecified eye. Use it when the record states pupillary margin degeneration but does not specify right or left.
Clinical signs
Clinical features vary; refer to documentation. Findings may include visible irregularity or atrophy at the pupillary border on eye examination, but the diagnosis should be supported by the ophthalmology note.
When to use this code
Use H21.249 when the provider documents degeneration of the pupillary margin and the affected eye is not identified. It may also fit follow-up visits when the condition is listed as an established diagnosis without laterality.
If the chart names a specific eye, code that laterality instead. Check documentation when the note uses broader iris or anterior segment terms, because those may require a different code.
Do not use for
Do not use this code for trauma, infection, or inflammatory iris disorders. Also avoid it when the record identifies a different iris abnormality or a specific eye side.
Coding tip
Confirm laterality in the ophthalmology note before assigning this unspecified-eye code.