ICD-10 Code H16.233 – Neurotrophic keratoconjunctivitis, bilateral (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code H16.233 – Neurotrophic keratoconjunctivitis, bilateral
What it is
Use this code for neurotrophic keratoconjunctivitis affecting both eyes. It describes corneal and conjunctival disease caused by reduced corneal sensation, leading to impaired surface healing.
Clinical signs
Typical findings include a reduced or absent corneal reflex, persistent epithelial defects, punctate staining, or corneal ulceration. Clinical features vary; refer to documentation.
When to use this code
Assign H16.233 when the record specifically documents neurotrophic keratoconjunctivitis in both eyes. Use it for bilateral corneal surface disease linked to impaired corneal innervation, not for a vague dry-eye complaint.
If the note only says keratitis, corneal ulcer, or conjunctivitis without the neurotrophic and bilateral detail, check documentation before coding. You need support for both the condition and laterality.
Do not use for
Do not use this code for unilateral disease or unspecified laterality. It also should not replace codes for other infectious, allergic, or nonspecific keratoconjunctivitis when neurotrophic disease is not documented.
Coding tip
Confirm both eyes are involved and that the provider documents neurotrophic etiology before assigning H16.233.