ICD-10 Code G37.1 – Central demyelination of corpus callosum (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Central demyelination of corpus callosum is G37.1.
2026 ICD-10-CM Diagnosis Code G37.1 – Central demyelination of corpus callosum

What it is

This code identifies a central demyelinating disorder involving the corpus callosum, the nerve fiber bridge between the brain hemispheres. It is used when documentation specifically names demyelination in this structure.

Clinical signs

Clinical features vary; refer to documentation. Patients may have neurologic deficits consistent with demyelinating disease, and imaging may show corpus callosum involvement.

When to use this code

Use G37.1 when the provider documents central demyelination of the corpus callosum as the diagnosis. You may also use it when imaging or specialist notes clearly support this specific condition and no broader demyelinating diagnosis is documented.

If the record only says “demyelinating disease” or names another neurologic disorder, check documentation before assigning this code. Code the most specific diagnosis supported by the chart.

Do not use for

Do not use this code for peripheral demyelinating neuropathies or nonspecific white-matter changes without documented corpus callosum demyelination. Check documentation if the condition is described only as suspected.

Coding tip

Assign this code only when the corpus callosum involvement is explicitly documented; otherwise, query or code the documented demyelinating condition.

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