ICD-10 Code G35.B2 – Non-active primary progressive multiple sclerosis (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Non-active primary progressive multiple sclerosis is G35.B2.
2026 ICD-10-CM Diagnosis Code G35.B2 – Non-active primary progressive multiple sclerosis

What it is

This code identifies primary progressive multiple sclerosis that is not currently active. Use it when documentation shows a progressive MS course without recent relapses or MRI activity.

Clinical signs

Clinical features vary; refer to documentation. Commonly, you may see steadily worsening neurologic deficits over time, such as gait difficulty, weakness, or spasticity, without evidence of recent inflammatory activity.

When to use this code

Use G35.B2 when the record specifically states non-active primary progressive MS. This is appropriate for follow-up visits, problem lists, or assessments describing progression without relapse or active disease. Check documentation if activity status is unclear.

Do not use for

Do not use this code for relapsing-remitting MS, active progressive MS, or unspecified MS. If the note does not clearly identify the subtype and activity status, check documentation.

Coding tip

Code the MS subtype and activity status exactly as documented; “non-active” is not interchangeable with “stable” unless the provider states it.

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