ICD-10 Code F16.2 – Hallucinogen dependence (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Hallucinogen dependence is F16.2.
2026 ICD-10-CM Diagnosis Code F16.2 – Hallucinogen dependence

What it is

F16.2 identifies dependence on hallucinogens, meaning a pattern of repeated use with impaired control and ongoing use despite harm. You use this code when the record supports a dependence diagnosis, not just prior use.

Clinical signs

Clinical features may include strong craving, difficulty cutting down, and continued use despite social, work, or health problems. Clinical features vary; refer to documentation.

When to use this code

Use F16.2 when the clinician documents hallucinogen dependence or a dependent pattern tied to substances such as LSD, psilocybin, or similar agents. Code it when the note supports dependence criteria, even if intoxication or withdrawal is also addressed. If the record only says use, abuse, or history of use, check documentation before assigning this code.

Do not use for

Do not use F16.2 for simple hallucinogen use without dependence, acute intoxication, or unspecified substance-related problems. If the chart does not clearly document dependence, check documentation.

Coding tip

Confirm the provider’s wording; dependence must be explicit or clearly supported in the note.

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