ICD-10 Code F14.22 – Cocaine dependence with intoxication (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Cocaine dependence with intoxication is F14.22.
2026 ICD-10-CM Diagnosis Code F14.22 – Cocaine dependence with intoxication

What it is

This code identifies cocaine dependence when the patient is also intoxicated. Use it when the record shows a dependence syndrome plus current cocaine intoxication.

Clinical signs

Clinical features vary; refer to documentation. Intoxication may include euphoria, agitation, talkativeness, impaired judgment, or sympathetic overactivity, while dependence reflects compulsive use and difficulty stopping.

When to use this code

Use F14.22 when the provider documents both cocaine dependence and intoxication during the same encounter. It may apply in emergency, inpatient, or behavioral health notes when intoxication is active and dependence is clearly stated.

If the note only says cocaine use, abuse, or intoxication without dependence, this code is not supported. Check documentation for the specific substance-related diagnosis and whether intoxication is current.

Do not use for

Do not use this code for cocaine abuse, cocaine use disorder without dependence, or remote history of cocaine use. If dependence is not documented, check documentation.

Coding tip

Code the dependence and intoxication only when both are explicitly documented in the assessment or discharge diagnosis.

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