ICD-10 Code E79 – Disorders of purine and pyrimidine metabolism (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Disorders of purine and pyrimidine metabolism is E79.
2026 ICD-10-CM Diagnosis Code E79 – Disorders of purine and pyrimidine metabolism

What it is

E79 identifies disorders that affect the body’s handling of purines and pyrimidines, the building blocks of nucleic acids. Use it for metabolic conditions in this category when the record does not specify a more exact diagnosis.

Clinical signs

Clinical features vary; refer to documentation. These disorders may be noted by abnormal uric acid metabolism, recurrent gout, or other inherited or acquired metabolic findings tied to purine or pyrimidine processing.

When to use this code

Use E79 when the provider documents a disorder of purine or pyrimidine metabolism without naming a more specific ICD-10-CM code. It may also fit unspecified metabolic conditions in this category when the chart supports the diagnosis. If the record identifies a specific inherited enzyme defect or another named disorder, code that condition instead.

Do not use for

Do not use this code for gout alone unless the provider links it to a purine metabolism disorder. Check documentation if the condition is better described by a more specific metabolic, renal, or hereditary diagnosis.

Coding tip

Review the assessment carefully and code the most specific documented metabolic disorder before defaulting to E79.

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