ICD-10 Code E78.8 – Other disorders of lipoprotein metabolism (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code E78.8 – Other disorders of lipoprotein metabolism
What it is
E78.8 is used for lipoprotein metabolism disorders that do not fit a more specific ICD-10 category. It covers documented abnormalities in lipoprotein handling or composition when the record does not name a different, more exact diagnosis.
Clinical signs
Clinical features vary; refer to documentation. You may see abnormal lipid testing, a charted lipoprotein disorder, or a clinician’s note describing an unspecified inherited or acquired lipoprotein abnormality.
When to use this code
Use E78.8 when the provider documents a lipoprotein metabolism disorder but does not specify a more precise type. It is appropriate when the condition is clearly identified in the record and not better captured by another E78 code. If the documentation only mentions dyslipidemia or hyperlipidemia without further detail, check documentation before assigning this code.
Do not use for
Do not use this code when the record supports a more specific lipid disorder, such as isolated hypercholesterolemia or hypertriglyceridemia. Do not use it for nonspecific abnormal lab results alone.
Coding tip
Code E78.8 only when the provider explicitly documents a lipoprotein metabolism disorder and no more specific diagnosis is available.