ICD-10 Code E67.2 – Megavitamin-B6 syndrome (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code E67.2 – Megavitamin-B6 syndrome
What it is
E67.2 identifies megavitamin-B6 syndrome, a condition caused by excessive vitamin B6 intake. Use it when documentation states B6 overuse, toxicity, or the named syndrome.
Clinical signs
Clinical features vary; refer to documentation. Standard references describe sensory neuropathy, numbness, tingling, and gait problems in vitamin B6 excess.
When to use this code
Use this code when the provider documents megavitamin-B6 syndrome or vitamin B6 toxicity from supplements or other sources. It may also apply when excessive pyridoxine use is clearly linked to the diagnosis.
Code it only when the record supports overexposure rather than routine supplementation. If the note is unclear about the vitamin involved, check documentation before assigning E67.2.
Do not use for
Do not use this code for general vitamin deficiency, nonspecific neuropathy, or adverse effects not tied to vitamin B6 excess. Check documentation if the record does not explicitly identify B6 overuse.
Coding tip
Look for explicit wording such as “vitamin B6 toxicity” or “megavitamin-B6 syndrome” before coding E67.2.