ICD-10 Code E53.1 – Pyridoxine deficiency (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code E53.1 – Pyridoxine deficiency
What it is
E53.1 identifies pyridoxine, or vitamin B6, deficiency. Use it when documentation shows a lack of this vitamin causing a deficiency state.
Clinical signs
Clinical features vary; refer to documentation. Commonly noted findings may include neurologic or skin-related manifestations, but you should code only when the record supports vitamin B6 deficiency.
When to use this code
Use E53.1 when the provider documents pyridoxine deficiency, vitamin B6 deficiency, or a deficiency state attributed to low pyridoxine. It may also fit when deficiency is being evaluated and clearly stated in the assessment. Check documentation if the note only mentions supplementation or nonspecific malnutrition.
Do not use for
Do not use this code for general vitamin deficiency without naming pyridoxine. Avoid it when the chart only documents dietary counseling, routine supplementation, or an unrelated neurologic disorder.
Coding tip
Code E53.1 only when the provider explicitly links the condition to pyridoxine or vitamin B6 deficiency.