ICD-10 Code E09.321 – Drug or chemical induced diabetes mellitus with mild nonproliferative diabetic retinopathy with macular edema (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code E09.321 – Drug or chemical induced diabetes mellitus with mild nonproliferative diabetic retinopathy with macular edema
What it is
This code identifies diabetes caused by a drug or chemical, along with mild nonproliferative diabetic retinopathy and macular edema in the eye. Use it when documentation links the diabetes and retinal findings to the same condition.
Clinical signs
Clinical features vary; refer to documentation. Mild nonproliferative retinopathy means early retinal vessel changes, and macular edema indicates fluid-related swelling in the macula that can affect central vision.
When to use this code
Use this code when the record states drug- or chemical-induced diabetes and specifically documents mild nonproliferative diabetic retinopathy with macular edema. You should code it only when the eye complication is clearly associated with the diabetes. Check documentation if the causative substance or retinal severity is not explicit.
Do not use for
Do not use this code for diabetes without a documented drug or chemical cause, or when retinopathy severity is different. If macular edema or the mild nonproliferative stage is not confirmed, choose a more specific or appropriate code.
Coding tip
Verify both the induced cause and the exact eye complication before assigning E09.321.