ICD-10 Code E08.331 – Diabetes mellitus due to underlying condition with moderate nonproliferative diabetic retinopathy with macular edema (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Diabetes mellitus due to underlying condition with moderate nonproliferative diabetic retinopathy with macular edema is E08.331.
2026 ICD-10-CM Diagnosis Code E08.331 – Diabetes mellitus due to underlying condition with moderate nonproliferative diabetic retinopathy with macular edema

What it is

This code identifies diabetes caused by another underlying condition, with moderate nonproliferative diabetic retinopathy affecting the retina and associated macular edema. Use it when the eye findings are documented as linked to the secondary diabetes.

Clinical signs

Documentation may note retinal microvascular changes, hemorrhages, exudates, or other findings consistent with moderate nonproliferative retinopathy. Macular edema means swelling in the macula; clinical features vary, so refer to documentation.

When to use this code

Use this code when the provider documents diabetes due to an underlying condition and specifies moderate nonproliferative diabetic retinopathy with macular edema in one or both eyes. It is appropriate for ophthalmology, endocrinology, or problem-list documentation that clearly supports the relationship.

Assign it only when the record links the retinopathy and edema to the diabetic condition. If laterality or severity is unclear, check documentation before coding.

Do not use for

Do not use this code for diabetic retinopathy without macular edema, for proliferative retinopathy, or when the diabetes is not due to an underlying condition. Check documentation for the correct diabetes category.

Coding tip

Verify both the diabetes type and the exact eye complication wording before assigning E08.331.

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