ICD-10 Code E05.10 – Thyrotoxicosis with toxic single thyroid nodule without thyrotoxic crisis or storm (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code E05.10 – Thyrotoxicosis with toxic single thyroid nodule without thyrotoxic crisis or storm
What it is
This code identifies thyrotoxicosis caused by one autonomous thyroid nodule. It applies when the nodule produces excess thyroid hormone and there is no thyrotoxic crisis or storm.
Clinical signs
Clinical features may include symptoms of hyperthyroidism such as weight loss, palpitations, tremor, heat intolerance, or anxiety. Imaging or endocrine evaluation typically shows a single toxic nodule; clinical features vary, refer to documentation.
When to use this code
Use this code when the provider documents thyrotoxicosis due to a single toxic thyroid nodule and specifically states there is no crisis or storm. It is appropriate for confirmed toxic adenoma cases managed in outpatient or inpatient settings. Verify that the record supports a single nodule rather than multinodular disease.
Do not use for
Do not use this code for thyrotoxicosis with toxic multinodular goiter, Graves’ disease, or nonspecific hyperthyroidism. Check documentation if the chart does not clearly identify a single toxic nodule.
Coding tip
Assign E05.10 only when the provider links thyrotoxicosis to a single toxic thyroid nodule and excludes thyroid storm.