ICD-10 Code D83.1 – Common variable immunodeficiency with predominant immunoregulatory T-cell disorders (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Common variable immunodeficiency with predominant immunoregulatory T-cell disorders is D83.1.
2026 ICD-10-CM Diagnosis Code D83.1 – Common variable immunodeficiency with predominant immunoregulatory T-cell disorders

What it is

D83.1 identifies a form of common variable immunodeficiency in which immune dysregulation, especially involving T-cell function, is the main documented feature. Use it when the diagnosis specifically includes predominant immunoregulatory T-cell disorders.

Clinical signs

Patients may have recurrent infections along with evidence of immune dysregulation, such as autoimmune or inflammatory complications. Clinical features vary; refer to documentation for the specific T-cell disorder described.

When to use this code

Use D83.1 when the provider documents common variable immunodeficiency with predominant immunoregulatory T-cell disorders, or clearly states CVID with this immune phenotype. It is appropriate when the record links the immunodeficiency to T-cell regulatory abnormalities rather than a nonspecific CVID diagnosis. Check documentation if the chart only says CVID, because another D83 category may fit better.

Do not use for

Do not use this code for unspecified common variable immunodeficiency or other antibody deficiencies without the T-cell disorder qualifier. If the record does not clearly support the specific subtype, check documentation.

Coding tip

Code the most specific CVID subtype documented; the presence of “predominant immunoregulatory T-cell disorders” is the key phrase to confirm.

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