ICD-10 Code D72.0 – Genetic anomalies of leukocytes (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code D72.0 – Genetic anomalies of leukocytes
What it is
D72.0 identifies inherited or congenital abnormalities affecting leukocytes, the white blood cells that support immune defense. Use it when documentation states a genetic defect or anomaly of leukocytes rather than an acquired disorder.
Clinical signs
Clinical features vary; refer to documentation. Findings may include recurrent infections, abnormal white blood cell morphology, or other evidence of impaired leukocyte function linked to a genetic cause.
When to use this code
Use D72.0 when the provider documents a congenital, hereditary, or genetic leukocyte abnormality as the diagnosis. It may also fit when records describe a specific inherited defect of leukocyte development or function and no more specific code is available.
Do not use for
Do not use this code for acquired leukocyte disorders, nonspecific abnormal blood counts, or transient infection-related changes. Check documentation if the record does not clearly state a genetic leukocyte anomaly.
Coding tip
Code the condition only when the chart explicitly links the leukocyte abnormality to a genetic or congenital cause.