ICD-10 Code D70.1 – Agranulocytosis secondary to cancer chemotherapy (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code D70.1 – Agranulocytosis secondary to cancer chemotherapy
What it is
D70.1 identifies agranulocytosis caused by cancer chemotherapy. Use it when neutrophil suppression is documented as a direct effect of antineoplastic treatment.
Clinical signs
Clinical features vary; refer to documentation. Commonly noted findings include severe neutropenia, increased infection risk, fever, or mucosal inflammation when clinicians diagnose chemotherapy-related agranulocytosis.
When to use this code
Use D70.1 when the provider links agranulocytosis to chemotherapy, including current treatment or a recent cycle. Code it from the record, not from assumption, and confirm the causal relationship is documented.
If the note only says “low white blood cells” or “neutropenia” without stating agranulocytosis, check documentation. You should also verify whether the condition is due to another cause, such as infection or another drug.
Do not use for
Do not use this code for agranulocytosis from non-chemotherapy drugs, radiation, or an unspecified cause. Check documentation if the record does not clearly connect the condition to cancer chemotherapy.
Coding tip
Always capture the provider’s stated cause; D70.1 depends on a documented chemotherapy relationship.