ICD-10 Code D56 – Thalassemia (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code D56 – Thalassemia
What it is
Thalassemia is a group of inherited blood disorders that reduce normal hemoglobin production. You use this code when the record identifies thalassemia without a more specific subtype.
Clinical signs
Clinical features vary; refer to documentation. Common findings include anemia, fatigue, pallor, and possible splenomegaly or growth delay in more severe forms.
When to use this code
Use D56 when the provider documents thalassemia and does not specify alpha, beta, or another subtype. It may also support coding when the note confirms a known thalassemia disorder under ongoing evaluation or follow-up.
If the record gives a specific type, choose the more detailed code instead. Check documentation for whether the condition is trait, minor, intermedia, or major, if stated.
Do not use for
Do not use this code for iron-deficiency anemia or other acquired anemias. Also avoid it when the documentation names a specific thalassemia subtype that has a more precise ICD-10-CM code.
Coding tip
Code to the highest documented specificity and confirm whether the provider means thalassemia trait, carrier state, or a confirmed disease.