ICD-10 Code D48.60 – Neoplasm of uncertain behavior of unspecified breast (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code D48.60 – Neoplasm of uncertain behavior of unspecified breast
What it is
D48.60 identifies a breast mass or lesion whose behavior is uncertain, meaning pathology or clinical workup has not shown whether it is benign or malignant. Use it when the record documents an unspecified breast neoplasm with unclear biologic behavior.
Clinical signs
Clinical features vary; refer to documentation. Patients may have a palpable breast lump, imaging abnormality, or tissue finding that prompts further evaluation, but the record does not confirm cancer or a benign diagnosis.
When to use this code
Use this code when the provider documents a neoplasm of uncertain behavior in the breast and no more specific site or behavior is stated. It also fits when pathology or imaging leaves the lesion indeterminate and the breast laterality or quadrant is not documented. Check documentation if a more specific code is available.
Do not use for
Do not use D48.60 for clearly benign breast lesions, confirmed malignant breast cancer, or inflammatory breast conditions. If the record identifies a specific benign, malignant, or laterality-based diagnosis, code that instead.
Coding tip
Query the provider for laterality and final behavior whenever the chart only says “breast mass” or “lesion,” because a more specific code may apply.