ICD-10 Code D43.0 – Neoplasm of uncertain behavior of brain, supratentorial (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code D43.0 – Neoplasm of uncertain behavior of brain, supratentorial
What it is
This code identifies a brain tumor in the supratentorial region when the pathology or behavior is uncertain. Use it when the record documents an intracranial neoplasm that cannot be classified as clearly benign or malignant.
Clinical signs
Clinical features vary; refer to documentation. Patients may present with headaches, seizures, focal neurologic deficits, or signs of increased intracranial pressure, depending on tumor size and location.
When to use this code
Use D43.0 when the provider documents a neoplasm of uncertain behavior involving the cerebrum or other supratentorial brain structures. It is appropriate for confirmed intracranial tumors with unclear biologic behavior, not for suspected masses without a definitive diagnosis. Check documentation for the exact site.
Do not use for
Do not use this code for benign or malignant brain tumors with specified behavior, or for lesions outside the supratentorial brain. If the chart only says “brain mass” or “rule out tumor,” check documentation.
Coding tip
Verify the anatomic site and the phrase “uncertain behavior” before assigning D43.0.