ICD-10 Code D25.1 – Intramural leiomyoma of uterus (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Intramural leiomyoma of uterus is D25.1.
2026 ICD-10-CM Diagnosis Code D25.1 – Intramural leiomyoma of uterus

What it is

D25.1 identifies a benign smooth muscle tumor, or fibroid, located within the muscular wall of the uterus. It is used when documentation specifies an intramural uterine leiomyoma.

Clinical signs

Clinical features vary; refer to documentation. Common references describe abnormal uterine bleeding, pelvic pressure, or an enlarged, irregular uterus, but the diagnosis should be supported by imaging or clinician assessment.

When to use this code

Use D25.1 when the provider documents an intramural leiomyoma, intramural fibroid, or a fibroid centered in the uterine myometrium. Code it when the record clearly distinguishes this location from submucosal, subserosal, or unspecified uterine leiomyoma. If the site is not stated, check documentation.

Do not use for

Do not use D25.1 for uterine leiomyomas with a different location, such as submucous or subserous tumors. Avoid this code when the chart only says “fibroid uterus” or “leiomyoma” without location.

Coding tip

Confirm the exact uterine location in the note or imaging report before assigning D25.1.

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