ICD-10 Code C90.02 – Multiple myeloma in relapse (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code C90.02 – Multiple myeloma in relapse
What it is
C90.02 identifies multiple myeloma that has returned after a period of remission or improvement. Use it when the record clearly states relapse or recurrent disease.
Clinical signs
Clinical features vary; refer to documentation. Common findings may include recurrent bone pain, anemia, renal impairment, or other evidence that the myeloma has become active again.
When to use this code
Use C90.02 when the provider documents relapsed multiple myeloma, recurrent myeloma, or return of disease after prior response. It fits follow-up visits, oncology assessments, and admissions where the relapse is the reason for care. Check documentation if the chart only says “history of myeloma” or “active myeloma” without relapse.
Do not use for
Do not use this code for newly diagnosed multiple myeloma or for remission status alone. If the note does not confirm relapse, check documentation before assigning C90.02.
Coding tip
Code the relapse only when the provider explicitly links the current encounter to recurrent myeloma.