ICD-10 Code C84.78 – Anaplastic Large Cell Lymphoma, ALK-Negative, Lymph Nodes of Multiple Sites (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code C84.78 – Anaplastic large cell lymphoma, ALK-negative, lymph nodes of multiple sites
What it is
This code identifies anaplastic large cell lymphoma that is ALK-negative and involves lymph nodes in more than one site. Use it for a documented nodal lymphoma diagnosis, not a broad lymphoma history.
Clinical signs
Clinical features vary; refer to documentation. Typical findings may include enlarged lymph nodes and other lymphoma-related signs, but the diagnosis should be confirmed in the medical record.
When to use this code
Use C84.78 when the provider documents ALK-negative anaplastic large cell lymphoma affecting lymph nodes at multiple sites. It is appropriate when the site is nodal and the record supports multifocal lymph node involvement. Check documentation if the note only says lymphoma or does not specify ALK status.
Do not use for
Do not use this code for ALK-positive disease, other lymphoma types, or lymphoma limited to a single nodal site. Check documentation if the record describes extranodal disease only.
Coding tip
Verify both ALK-negative status and multiple lymph node sites before assigning C84.78.