ICD-10 Code C84.68 – Anaplastic large cell lymphoma, ALK-positive, lymph nodes of multiple sites (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Anaplastic large cell lymphoma, ALK-positive, lymph nodes of multiple sites is C84.68.
2026 ICD-10-CM Diagnosis Code C84.68 – Anaplastic large cell lymphoma, ALK-positive, lymph nodes of multiple sites

What it is

This code identifies anaplastic large cell lymphoma that is ALK-positive and involves lymph nodes at multiple sites. Use it when the diagnosis is confirmed and the site is documented as multiple nodal regions.

Clinical signs

Findings often include enlarged lymph nodes, systemic “B” symptoms, or other lymphoma-related manifestations. Clinical features vary; refer to documentation for ALK status and nodal distribution.

When to use this code

Use this code when the record clearly states ALK-positive anaplastic large cell lymphoma and specifies involvement of lymph nodes of multiple sites. It is appropriate for confirmed lymphoma diagnoses on pathology, oncology, or discharge documentation. If the site is not documented, check documentation.

Do not use for

Do not use this code for ALK-negative disease, unspecified anaplastic large cell lymphoma, or lymphoma limited to a single nodal region. If the diagnosis is uncertain or not confirmed, do not code it as established lymphoma.

Coding tip

Verify both ALK-positive status and the “multiple sites” lymph node location before assigning C84.68.

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