ICD-10 Code C84.48 – Peripheral T-cell lymphoma, not elsewhere classified, lymph nodes of multiple sites (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code C84.48 – Peripheral T-cell lymphoma, not elsewhere classified, lymph nodes of multiple sites
What it is
This code identifies peripheral T-cell lymphoma, not otherwise specified, involving lymph nodes in multiple sites. It is used when the diagnosis is confirmed and the nodal distribution is documented as multifocal.
Clinical signs
Clinical features vary; refer to documentation. Common findings in nodal lymphoma include enlarged lymph nodes at more than one site, sometimes with systemic “B” symptoms such as fever, night sweats, or weight loss.
When to use this code
Use C84.48 when the provider documents peripheral T-cell lymphoma, not elsewhere classified, and specifies lymph nodes of multiple sites. Apply it for confirmed nodal disease affecting more than one region, whether at diagnosis or follow-up, if the condition remains active and documented.
Do not assume this code from a generic lymphoma note. Check documentation for the exact lymphoma type and the multi-site lymph node involvement before assigning the code.
Do not use for
Do not use this code for other T-cell lymphomas, unspecified lymphoma, or disease limited to a single lymph node site. Check documentation if the record does not clearly state peripheral T-cell lymphoma, not elsewhere classified.
Coding tip
Match both the histologic type and the anatomic site; if either is unclear, query the provider before coding.