ICD-10 Code C83.10 – Mantle cell lymphoma, unspecified site (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Mantle cell lymphoma, unspecified site is C83.10.
2026 ICD-10-CM Diagnosis Code C83.10 – Mantle cell lymphoma, unspecified site

What it is

C83.10 identifies mantle cell lymphoma when the record does not specify the anatomic site. It is a B-cell non-Hodgkin lymphoma that arises from mantle zone lymphocytes.

Clinical signs

Clinical features vary; refer to documentation. Common findings include lymphadenopathy, splenomegaly, and systemic “B” symptoms such as fever, night sweats, or weight loss.

When to use this code

Use C83.10 when the provider documents mantle cell lymphoma but does not identify a specific site or nodal region. Apply it for confirmed diagnoses in the current encounter or problem list when no more specific code is supported. If the record later specifies site, code that documented location instead.

Do not use for

Do not use this code for other non-Hodgkin lymphomas, Hodgkin lymphoma, or leukemias. Do not assign it when the chart specifies a more exact mantle cell lymphoma site.

Coding tip

Check the pathology and oncology notes for site detail before defaulting to the unspecified code.

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