ICD-10 Code C82.57 – Diffuse follicle center lymphoma, spleen (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Diffuse follicle center lymphoma, spleen is C82.57.
2026 ICD-10-CM Diagnosis Code C82.57 – Diffuse follicle center lymphoma, spleen

What it is

C82.57 identifies diffuse follicle center lymphoma involving the spleen. Use it when the record documents this specific indolent B-cell lymphoma in splenic tissue.

Clinical signs

Clinical features vary; refer to documentation. Splenic involvement may be noted on imaging, pathology, or specialist assessment, often with findings consistent with follicle center lymphoma.

When to use this code

Use this code when the provider clearly documents diffuse follicle center lymphoma of the spleen. It is appropriate for confirmed splenic disease, including pathology-supported diagnoses or oncology notes naming the spleen as the involved site.

If the record only says follicle center lymphoma without site detail, check documentation before coding. You should also verify whether the spleen is the primary documented site or part of a broader lymphoma description.

Do not use for

Do not use this code for unspecified follicular lymphoma, other lymphoma subtypes, or splenic enlargement without a lymphoma diagnosis. Check documentation if the site or histology is unclear.

Coding tip

Code the exact lymphoma subtype and site as documented; if the spleen is not explicitly named, do not assume C82.57.

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