ICD-10 Code C78.80 – Secondary malignant neoplasm of unspecified digestive organ (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Secondary malignant neoplasm of unspecified digestive organ is C78.80.
2026 ICD-10-CM Diagnosis Code C78.80 – Secondary malignant neoplasm of unspecified digestive organ

What it is

This code identifies metastatic cancer involving a digestive organ, but the exact site is not specified. Use it when documentation confirms secondary malignant disease in the digestive system without naming the organ.

Clinical signs

Clinical features vary by the involved digestive organ and primary cancer site; refer to documentation. Findings may reflect metastatic disease on imaging, biopsy, or pathology, but the exact organ is not identified.

When to use this code

Use C78.80 when the record states secondary malignant neoplasm of a digestive organ and does not specify stomach, liver, pancreas, bowel, or another site. It also fits when the provider documents metastatic digestive involvement without further detail. Check documentation if the primary site is unclear.

Do not use for

Do not use this code for primary digestive cancers or for secondary malignant neoplasms with a specified digestive organ code. If the chart names the organ, code the more specific site instead.

Coding tip

Assign the most specific metastatic site documented, and query when “digestive organ” is the only location provided.

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