ICD-10 Code C77.8 – Secondary and unspecified malignant neoplasm of lymph nodes of multiple regions (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Secondary and unspecified malignant neoplasm of lymph nodes of multiple regions is C77.8.
2026 ICD-10-CM Diagnosis Code C77.8 – Secondary and unspecified malignant neoplasm of lymph nodes of multiple regions

What it is

This code identifies metastatic malignant disease involving lymph nodes in more than one region, when the primary cancer is elsewhere or not specified. Use it for secondary nodal spread, not for a primary lymphoma.

Clinical signs

Clinical features vary; refer to documentation. Imaging, biopsy, or pathology may show malignant involvement of multiple lymph node regions, and records often note known metastatic cancer with nodal spread.

When to use this code

Use C77.8 when the provider documents secondary malignant neoplasm in multiple lymph node regions. It fits cases where metastasis to several nodal areas is confirmed or clearly stated. Code the primary malignancy first when it is known and active.

Do not use for

Do not use this code for primary lymph node cancers, such as lymphoma, or for benign lymphadenopathy. If the record only says enlarged nodes without malignancy, Check documentation.

Coding tip

Confirm that “secondary,” “metastatic,” or similar wording is documented and that more than one nodal region is involved.

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