ICD-10 Code C72.3 – Malignant neoplasm of optic nerve (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code C72.3 – Malignant neoplasm of optic nerve
What it is
C72.3 identifies a malignant tumor arising in the optic nerve. Use it when documentation states primary cancer of the optic nerve or a malignant optic nerve neoplasm.
Clinical signs
Clinical features vary; refer to documentation. Commonly reported findings include visual loss, optic disc changes, proptosis, or evidence of optic nerve involvement on imaging or pathology.
When to use this code
Use C72.3 when the provider documents a malignant neoplasm of the optic nerve, whether newly diagnosed or under active evaluation. It also fits confirmed primary optic nerve cancer in the assessment, problem list, or pathology report.
If the note only says “optic nerve lesion” or “optic neuropathy,” check documentation before assigning this code. Confirm that the record specifically supports malignancy and the optic nerve as the site.
Do not use for
Do not use C72.3 for benign optic nerve tumors, non-neoplastic optic neuropathy, or metastatic disease to the optic nerve unless the provider documents a primary malignant optic nerve neoplasm. Check documentation.
Coding tip
Code from the provider’s exact wording and verify laterality or primary site details elsewhere in the record if they are needed.