ICD-10 Code C17.0 – Malignant neoplasm of duodenum (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code C17.0 – Malignant neoplasm of duodenum
What it is
C17.0 identifies a malignant tumor arising in the duodenum, the first part of the small intestine. Use it when documentation states a primary cancer of the duodenum.
Clinical signs
Clinical features vary; refer to documentation. Patients may have abdominal pain, weight loss, nausea, vomiting, or gastrointestinal bleeding, but the diagnosis depends on confirmed malignancy of the duodenum.
When to use this code
Use C17.0 when the provider documents primary malignant neoplasm of the duodenum, including biopsy-confirmed cancer or a clearly stated diagnosis. It also applies when the record specifies duodenal origin rather than spread from another site. Check documentation if the site is uncertain.
Do not use for
Do not use this code for benign duodenal tumors, polyps, or inflammatory conditions. Also avoid it when the cancer is documented as metastatic to the duodenum rather than primary there.
Coding tip
Verify the exact anatomic site and whether the malignancy is primary or secondary before assigning C17.0.