ICD-10 Code B57.49 – Other nervous system involvement in Chagas’ disease (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Other nervous system involvement in Chagas’ disease is B57.49.
2026 ICD-10-CM Diagnosis Code B57.49 – Other nervous system involvement in Chagas’ disease

What it is

This code identifies Chagas’ disease when the infection affects the nervous system in a way not captured by a more specific code. Use it for documented neurologic involvement linked to Trypanosoma cruzi infection.

Clinical signs

Clinical features vary; refer to documentation. Neurologic involvement may include signs of central or peripheral nervous system disease, but you should code only when the record clearly connects the findings to Chagas’ disease.

When to use this code

Use B57.49 when the provider documents Chagas’ disease with nervous system involvement and does not specify another Chagas neurologic category. It also fits cases where the chart describes neurologic complications from Chagas without a more exact designation. Check documentation for the exact manifestation.

Do not use for

Do not use this code for Chagas’ disease without nervous system involvement, or when a different organ system is specified. If the neurologic condition is unrelated or the cause is unclear, choose another diagnosis code.

Coding tip

Link the neurologic findings to Chagas’ disease in the provider note before assigning B57.49.

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