ICD-10 Code B08.22 – Exanthema subitum [sixth disease] due to human herpesvirus 7 (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Exanthema subitum [sixth disease] due to human herpesvirus 7 is B08.22.
2026 ICD-10-CM Diagnosis Code B08.22 – Exanthema subitum [sixth disease] due to human herpesvirus 7

What it is

B08.22 identifies exanthema subitum, also called sixth disease, when documentation specifies human herpesvirus 7 as the cause. Use it for this viral childhood illness, not for nonspecific fever or rash alone.

Clinical signs

Typical features include a sudden febrile illness followed by a rash as fever resolves. Clinical features vary; refer to documentation for the confirmed viral cause and any associated findings.

When to use this code

Use this code when the provider documents sixth disease or roseola specifically linked to human herpesvirus 7. It also fits when the record clearly states HHV-7 as the etiologic agent. If the cause is not specified, check documentation before coding.

Do not use for

Do not use B08.22 for exanthema subitum due to another virus or for an unspecified viral exanthem. Do not assign it when the chart only says fever and rash without a confirmed diagnosis.

Coding tip

Code the documented cause exactly; if HHV-7 is not named, verify whether a different exanthem code is more appropriate.

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