ICD-10 Code A81.81 – Kuru (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code A81.81 – Kuru
What it is
Kuru is a rare, fatal prion disease that affects the brain and nervous system. Use this code for documented kuru, not for other neurologic disorders.
Clinical signs
Clinical features vary; refer to documentation. Typical findings include progressive neurologic decline, tremor, ataxia, and loss of coordination, with worsening speech and swallowing problems.
When to use this code
Use A81.81 when the provider documents kuru by name or clearly confirms the diagnosis. It may appear in records describing a prion disease with compatible neurologic findings and a documented exposure history.
If the chart only mentions unexplained dementia, gait disturbance, or other nonspecific neurologic symptoms, do not assign this code without confirmation. Check documentation for the exact diagnosis and any supporting specialist assessment.
Do not use for
Do not use this code for other prion diseases, generic encephalopathy, or undiagnosed movement disorders. If the record does not specifically identify kuru, check documentation.
Coding tip
Verify the provider’s exact wording, because kuru is rare and should not be inferred from symptoms alone.