ICD-10 Code A41.59 – Other Gram-negative sepsis (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Other Gram-negative sepsis is A41.59.
2026 ICD-10-CM Diagnosis Code A41.59 – Other Gram-negative sepsis

What it is

A41.59 identifies sepsis caused by gram-negative organisms not named by a more specific ICD-10 code. Use it when the record documents gram-negative sepsis, but the organism is not otherwise classified.

Clinical signs

Clinical features vary; refer to documentation. Sepsis is typically documented with systemic infection and organ dysfunction, and the source or causative gram-negative organism may be noted in the chart.

When to use this code

Use A41.59 when the provider documents sepsis due to a gram-negative bacterium and no more specific code applies. It also fits when the organism is identified only as gram-negative or is listed as another gram-negative species. Check documentation for any additional infection site or organism-specific code.

Do not use for

Do not use this code for sepsis caused by a specifically coded organism when a more precise option is available. Do not use it for simple gram-negative infection without sepsis. Check documentation if the record is unclear.

Coding tip

Look for the provider’s exact wording and code the organism as specifically as the documentation allows.

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