ICD-10 Code A40.3 – Sepsis due to Streptococcus pneumoniae (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Sepsis due to Streptococcus pneumoniae is A40.3.
2026 ICD-10-CM Diagnosis Code A40.3 – Sepsis due to Streptococcus pneumoniae

What it is

A40.3 identifies sepsis caused by Streptococcus pneumoniae. Use it when the record supports a systemic infection due to this organism, not just a localized pneumococcal infection.

Clinical signs

Clinical features vary; refer to documentation. Sepsis is typically documented with systemic infection and organ dysfunction or a clinician’s explicit diagnosis of sepsis due to pneumococcus.

When to use this code

Use A40.3 when the provider states sepsis is due to Streptococcus pneumoniae, or when documentation clearly links the septic episode to that organism. It is appropriate for inpatient or outpatient coding when the diagnosis is confirmed in the record. Check documentation for any additional infection or organ dysfunction codes needed.

Do not use for

Do not use this code for pneumococcal pneumonia, bacteremia, or localized infection without sepsis. If the organism or sepsis relationship is not documented, check documentation before assigning A40.3.

Coding tip

Always code the organism and any associated organ dysfunction exactly as documented, and do not infer sepsis from culture results alone.

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