ICD-10 Code B25.8 – Other cytomegaloviral diseases (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Other cytomegaloviral diseases is B25.8.
2026 ICD-10-CM Diagnosis Code B25.8 – Other cytomegaloviral diseases

What it is

B25.8 identifies cytomegalovirus disease that is documented but does not fit the more specific CMV categories. Use it for clinically significant CMV infection when the record does not name a different site or manifestation.

Clinical signs

Clinical features vary; refer to documentation. CMV disease may present with systemic illness or organ-specific findings, but you should code only when the record supports active disease rather than simple exposure or past infection.

When to use this code

Use B25.8 when the provider documents “other cytomegaloviral disease,” “CMV disease,” or a CMV-related condition that is not described by a more specific ICD-10 code. It is also appropriate when the chart confirms CMV involvement but the exact manifestation is not further specified. Check documentation if the record is unclear.

Do not use for

Do not use this code for CMV exposure, carrier status, or seropositivity without active disease. If a more specific CMV diagnosis is documented, code that instead.

Coding tip

Look for the provider’s exact wording and code the most specific CMV diagnosis supported by the record.

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