ICD-10 Code A06.81 – Amebic cystitis (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code A06.81 – Amebic cystitis
What it is
A06.81 identifies cystitis caused by Entamoeba histolytica infection. Use it when the bladder inflammation is documented as amebic, not when the cause is unspecified or another infection.
Clinical signs
Clinical features vary; refer to documentation. Typical cystitis findings may include urinary frequency, urgency, dysuria, or suprapubic discomfort, with evidence linking the bladder inflammation to amebic infection.
When to use this code
Use A06.81 when the record clearly states amebic cystitis, or when the provider documents bladder involvement due to Entamoeba histolytica. You should also use it when a confirmed amebic infection is specifically tied to the urinary bladder in the assessment.
If the note only says cystitis without an infectious cause, check documentation before coding this diagnosis. Do not assume amebic involvement from travel history, gastrointestinal amebiasis, or nonspecific urinary symptoms alone.
Do not use for
Do not use A06.81 for ordinary bacterial cystitis, interstitial cystitis, or urinary symptoms without documented amebic infection. Check documentation if the chart does not clearly connect the bladder condition to amebiasis.
Coding tip
Code A06.81 only when the provider explicitly documents amebic cystitis or equivalent wording tying bladder disease to amebiasis.